Human Urine Proteomics: Analytical Techniques and Clinical Applications in Renal Diseases
نویسندگان
چکیده
منابع مشابه
advances in proteomics analytical techniques
proteins are fundamental components of cells which mediate many essential biological processes. proteomics is a rapidly growing field for the study of proteome, the protein complement expressed by the genome of an organism or cell type. the large-scale analysis of proteins leads to a more comprehensive view of molecular and cellular pathways that improves the overall understanding of the comple...
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Urine has become one of the most attractive biofluids in clinical proteomics as it can be obtained non-invasively in large quantities and is stable compared with other biofluids. The urinary proteome has been studied by almost any proteomics technology, but mass spectrometry-based urinary protein and peptide profiling has emerged as most suitable for clinical application. After a period of desc...
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The technology platforms for proteome analysis have advanced considerably over the last few years. Due to these improvements the number of studies on the analysis of the proteome/peptidome with the aim of defining biomarkers has escalated. In this review, we will summarise the technical aspects that relate to the proteomics field targeting the discovery of biomarkers for disease diagnosis. We w...
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ژورنال
عنوان ژورنال: International Journal of Proteomics
سال: 2015
ISSN: 2090-2166,2090-2174
DOI: 10.1155/2015/782798